Annual report pursuant to Section 13 and 15(d)

Going Concern and Management's Plans (Details Narrative)

v3.5.0.2
Going Concern and Management's Plans (Details Narrative) - USD ($)
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Cash and cash equivalents $ 189,231 $ 1,627,062 $ 7,837,339
Working capital deficiency 14,437,434    
Accumulated deficit 73,372,655 64,738,131  
Net loss 8,244,924 $ 23,229,319  
March 11, 2016 [Member] | Securities Purchase Agreements [Member]      
Aggregate equity financing 3,000,000    
Payment of closing amount 750,000    
Milestone payable amount 2,250,000    
Payment of securities purchase amount 1,367,120    
June, 2016 [Member] | Sixty-Day Convertible Notes [Member]      
Debt principal amount 400,000    
July, 2016 [Member] | Sixty-Day Convertible Notes [Member]      
Debt principal amount $ 400,000